Escherichia coli DNA repair genes radA and sms are the same gene

Document Type

Article

Publication Title

Journal of Bacteriology

Abstract

Escherichia coli strains carrying radA100 or sms mutations were identical in their sensitivities to either methyl methanesulfonate or UV radiation treatment and in their plasmid complementation patterns for UV radiation survival. DNA sequencing analysis of the radA mutant and radA+ strains and comparison of their sequences with the published sins gene sequence showed the radA mutant to differ only by a G-to-A transition mutation, which is predicted to change a cysteine in a zinc-finger motif to tyrosine. The sms gene is concluded to be identical to the previously described radA gene.

First Page

5045

Last Page

5048

DOI

10.1128/jb.178.16.5045-5048.1996

Publication Date

1-1-1996

This document is currently not available here.

Share

COinS