Effect of Phytochemical Compounds on Trichomonas tenax, an Oral Protozoan

Document Type

Article

Publication Title

Alternative Therapies In Health And Medicine

Abstract

Abstract

Trichomonas tenax is an oral protozoan with an estimated global pooled prevalence of 17% in the human population.1 Observational studies have demonstrated a significant statistical correlation between oral colonization by T. tenax and the progression of periodontal disease.2 Proposed pathogenic mechanisms for this protozoan include the production of tissue-damaging enzymes, induction of apoptosis in human cells, and dysbiosis of the oral microbiome.3 In patients for whom metronidazole (MTZ) is contraindicated, phytochemicals may offer a viable alternative for controlling T. tenax. Various plant extracts have shown promising in vitro activity against other trichomonads, such as T. vaginalis and Tritrichomonas foetus, as reviewed by Friedman et al.4.

First Page

6

Last Page

8

Publication Date

3-2024

Comments

Stuart, M. K., Motes, H. C., & Hudman, D. A. (2024). Effect of Phytochemical Compounds on Trichomonas tenax, an Oral Protozoan. Alternative therapies in health and medicine, 30(3), 6–8.

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