Dental status and risk of odontogenic complication in patients undergoing hematopoietic stem cell transplant
Document Type
Article
Publication Title
Supportive Care in Cancer
Abstract
Purpose: Dental evaluation and management prior to hematopoietic stem cell transplant (HSCT) plays a vital role in identifying and treating infections that may be life-threatening. The purpose of this study is to describe the dental management of patients undergoing pre-HSCT examination with the Dental Service at Memorial Sloan Kettering Cancer Center (MSKCC) and to report on odontogenic complications. Methods: Patients referred for evaluation as part of the standard preparation for HSCT were included. Following clinical and radiological examination, patients were assigned to one of three groups based on risk of odontogenic infection, and treatment was provided as indicated. Patients were followed, and their medical records were reviewed for odontogenic complications during the transplant admission. Results: Of the 375 patients evaluated, 350 patients underwent HSCT: allogeneic 143 (40.9%) and autologous 207 (59.1%). The distribution of primary cancer diagnosis was as follows: multiple myeloma 104 (29.7%), leukemias 95 (27.1%), Hodgkin’s lymphoma 28 (8.0%), non-Hodgkin’s Lymphoma 99 (28.3%), and other conditions 24 (6.9%). The median time from dental evaluation to transplant was 29 days. The median Decayed, Missing, Filled Teeth Index was 17. The median Community Periodontal Index was 1. Based on dental status, 145 patients (41.4%) were classified as low risk, 133 (38%) as moderate risk and 72 (20.6%) as high risk of odontogenic infection. One hundred fourteen patients (32.6%) required dental treatment prior to HSCT, and 100 of these (28.6%) completed treatment. Two (0.57%) patients had odontogenic complications. Conclusions: With conservative pre-HSCT dental treatment based on an infection risk classification system, a low odontogenic complication rate was observed.
First Page
2231
Last Page
2238
DOI
10.1007/s00520-020-05733-1
Publication Date
4-1-2021
Recommended Citation
Hansen, Heidi J.; Estilo, Cherry; Owosho, Adepitan; Solano, Armand Karl; Randazzo, Joseph; Huryn, Joseph; and Yom, Sae Hee K., "Dental status and risk of odontogenic complication in patients undergoing hematopoietic stem cell transplant" (2021). MOSDOH Faculty Publications. 98.
https://scholarworks.atsu.edu/mosdoh-faculty/98