Enhanced silver diamine fluoride therapy using the pilp method —a nanoindentation study
Document Type
Article
Publication Title
Dental Materials Journal
Abstract
The aim of this study was to evaluate the feasibility of applying the polymer-induced liquid-precursor (PILP) method to enhance silver diamine fluoride (SDF) therapy. One hundred forty micrometer deep artificial caries lesions were treated with (A) 38% SDF solution and (B) 38% SDF containing poly-L-aspartic acid (pASP). Changes in the nanomechanical profile across the lesion were evaluated. Hydrated artificial lesions had a low reduced elastic modulus (0.3 GPa) and nanohardness (0.02 GPa) region extending about 100 μm into the lesion, with a gradual linear increase to about 168 μm where the values plateaued to around 18 GPa/1.0 GPa. Topical application of SDF resulted in significantly recovered properties (p<0.001). SDF containing pASP resulted in greater nanomechanical properties compared to SDF alone, showing similar sloped regions up to 96 µm, then SDF alone dropped while SDF containing pASP continued at a modest slope until reaching normal at 144 µm. This nanoindentation study shows enhanced SDF therapy using the PILP method.
First Page
1009
Last Page
1015
DOI
10.4012/dmj.2019-273
Publication Date
1-1-2020
Recommended Citation
Nurrohman, Hamid; Habelitz, Stefan; Saeki, Kuniko; Sadr, Alireza; Gower, Laurie B.; Pazdernik, Vanessa; Tagami, Junji; Marshall, Sally J.; and Marshall, Grayson W., "Enhanced silver diamine fluoride therapy using the pilp method —a nanoindentation study" (2020). MOSDOH Faculty Publications. 114.
https://scholarworks.atsu.edu/mosdoh-faculty/114