Recognizing and Managing Isotretinoin-Induced Acne Fulminans without Systemic Symptoms

Document Type

Article

Publication Title

Journal of Dermatology for Physician Assistants

Abstract

Abstract

This report describes the case of a 14-year-old female patient who presented with severe nodulocystic acne on the face that started 6 to 8 weeks into treatment with isotretinoin. The patient complained of intermittent arthralgias but denied other systemic symptoms. She was diagnosed with acne fulminans without systemic symptoms induced by isotretinoin. She discontinued this medication and began a prolonged prednisone taper. As this began to mitigate the acute inflammation, isotretinoin was re-initiated and gradually up-titrated to induce long-term control of her acne. Acne fulminans has multiple clinical manifestations, thus making it difficult to distinguish at times. Management of this condition can also be challenging and requires a personalized approach. Isotretinoin-induced acne fulminans is increasing in incidence due to more widespread treatment of acne vulgaris with this medication. The prompt recognition and management of this adverse effect of isotretinoin can prevent it from progressing into fulminant disease, and diminish the number of disfiguring scars.

First Page

19

Last Page

23

DOI

10.58744/001c.70405

Publication Date

12-2022

Comments

Marsh, Bryn M. MPAS, PA-C1,a. Recognizing and Managing Isotretinoin-Induced Acne Fulminans without Systemic Symptoms. Journal of Dermatology for Physician Assistants 16(1):p 19-23, Winter 2022.

DOI: 10.58744/001c.70405

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