Management of Cyclosporine-Influenced Gingival Enlargement With Azithromycin
Document Type
Article
Publication Title
Clinical advances in periodontics
Abstract
INTRODUCTION: Management of drug-influenced gingival enlargement is challenging, and surgery is most often indicated. However, because of a unique mechanism of action, azithromycin helps in the management of gingival enlargement caused by cyclosporine. An incidental observation of the effect of azithromycin in the cyclosporine-influenced gingival enlargement by physicians in 1995 led to series of basic investigations and clinical trials confirming this observation and providing a non-surgical treatment modality. CASE PRESENTATION: In this report, successful management of cyclosporine-influenced gingival enlargement in a 39-year-old renal transplant patient with the use of azithromycin without any surgical intervention is presented. CONCLUSION: Use of azithromycin for managing cyclosporine-influenced gingival enlargement is a useful alternative or adjunct to surgical management. It is hoped that this report will raise further awareness of this non-surgical modality in patients taking cyclosporine.
First Page
140
Last Page
144
DOI
10.1002/cap.10097
Publication Date
9-1-2020
Recommended Citation
Kumar, Satish S.; Mohammad, Husain; and Kar, Kian, "Management of Cyclosporine-Influenced Gingival Enlargement With Azithromycin" (2020). ASDOH Faculty Publications. 126.
https://scholarworks.atsu.edu/asdoh-faculty/126